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Aspirin or Nitric Oxide

Which is Better for Reducing the Risk of Blood Clots?

AspirinOn Monday, August 31, 2009 Yahoo Health had an article entitled “Daily aspirin may do more harm than good: study” in which researchers found that:

“. . . the risks of bleeding from taking aspirin were such that its routine use in healthy people ‘cannot be supported’ – although they did not dispute its use in patients with a history of vascular problems.”

The title of the study was Aspirin for Asymptomatic Atherosclerosis and was funded, in part, by the British Heart Foundation.  The lead researcher was Professor Gerry Fowkes from the Wolfson Unit for Prevention of Peripheral Vascular Disease in Edinburgh, Scotland.  It involved 3,350 men and women aged 50 to 75 years old who had low ankle brachial indexes but no symptoms of heart disease or history of heart attack.  Study subjects were given either a daily 100 mg dose of aspirin or a placebo and evaluated over an eight year period.  The results were that there was no significant difference between the two groups in the number of heart attacks, strokes and other cardiovascular events suffered.  However, major bleeding that required hospitalization occurred in 2.0% of the aspirin group but only 1.2% in the placebo group.

This study was presented at the European Society of Cardiology Congress in Barcelona.  According to Professor Peter Weissberg, medical director of the British Heart Foundation:

“We know that patients with symptoms of artery disease, such as angina, heart attack or stroke, can reduce their risk of further problems by taking a small dose of aspirin each day.  The findings of this study agree with our current advice that people who do not have symptomatic or diagnosed artery or heart disease should not take aspirin, because the risks of bleeding may outweigh the benefits.”

Part of the rational for this study was the conflicting data regarding the use of aspirin for the primary prevention of cardiovascular events.  For example, in the Physician’s Health Study low-dose aspirin reduced the risk of a first myocardial infarction by 44% when compared with a placebo.  But, in the Women’s Health Study there was no significant difference in major cardiovascular events other than strokes.

What Does Nitric Oxide Have to Do Blood Clots?

The endothelial cells line all of your cardiovascular system.  One of their functions is to produce a molecule called Nitric Oxide (NO) which is critical in the proper control of blood pressure.  NO also inhibits platelet adhesion, activation, secretion and aggregation, as well as promoting platelet disaggregation.  This is extremely important in preventing blood clots in the vascular system that can lead to heart attacks and strokes.  It is also a critical factor in sickle cell anemia to help prevent red blood cells from changing, adhering to each other and clinging to the vascular walls.  This helps to prevent blockages which cause most of the pain and tissue damage associated with sickle cell anemia.

Even though your body uses NO to prevent blood clotting, it’s interesting to note that the endothelial cells are also necessary for blood to clot.  They synthesize the vitally important molecule called Factor VIII or von Willibrand’s Factor which is essential for blood clotting.  Without this molecule a person could bleed to death from a simple scratch.

A Final Consideration!

Aspirin is a drug and it has the potential for other side effects besides the risk of bleeding.  Some of the most common side effects are stomach pain, heart burn, nausea and vomiting.  Aspirin is one of the leading causes of gastrointestinal tract complications which include micro-bleeding and ulcers. 

If a person wants to reduce their risk for blood clotting then the proper repair of and support for the endothelial cells is vitally important.  Clinical studies have shown that a well designed L-arginine/Nitric Oxide protocol can repair the endothelial cells.  This allows them the perform one of their primary functions which is to keep the blood flowing without the danger of blot clotting.   

Together we can work to save a million lives!

Dan Hammer

The information contained in this blog is for general information purposes only and never as a substitute for professional medical advice or medical exam.  The information contain in this blogging website has not been evaluated by the Food and Drug Administration and should not be used to diagnose, treat, cure or prevent any disease without the supervision of a qualified medical doctor. 

8 comments to Aspirin or Nitric Oxide

  • Great information. Proargi is much better than aspirin!!

  • Thank you Steve. I absolutely agree with you that Proargi-9 Plus does a much better job than aspirin and all without side effects. Dan

  • my uncle got stomach ulcers because he took a lot of Aspirin to take care of his high blood pressure.;-.

  • Luke

    Have you heard of Niteworks? It’s endorsed by Louis Ignarro, the guy who won the Nobel Prize for the research that you refer to.

  • Hollie – Sorry to hear about your uncle’s stomach ulcers. I hope he is doing better. While aspirin certainly has benefits there are also risks as the above article points out. Improved nitric oxide production would have provided the same benefit but without the side effects. Thus, restoring the health of your endothelial cells that line all of your cardiovascular system is critically important. This enables the endothelial cells to properly produce nitric oxide which both relaxes the smooth muscles of the vascular walls to moderate blood pressure and keeps blood platelet cells from sticking together. Net result – lower blood pressure and reduced risk for blockages in the blood stream without any adverse health reactions. Dan

  • Hi Luke,
    Yes, I have heard of Niteworks. Dr. Ignarro received the 1998 Nobel Prize in Medicine with two other American researchers for discovery of how the endothelial cells produce nitric oxide – the master signaling molecule for the cardiovascular system. Both Niteworks and ProArgi-9 Plus utilize this Nobel Prize winning research in the design of their products. Dan

  • I hope you will keep updating your content constantly as you have one dedicated reader here.

  • Hi Rosendo,
    Thank you for being a dedicated reader. I’m doing me best to continue to add great content. I just need to do a better job on answering the comments left to me. It will be one of my New Year’s Resolutions.
    Dan

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